[Chondromyxoid fibroma]

Abstract

Chondromyxoid fibroma is a benign chondroid tissue tumor characterized by the lobular overgrowth of stellate or elongated cells in the myxoid or chondroid intracellular matrix. There may be giant multinucleate cells. They may be encountered in any skeletal bones, mainly at the age of 20-30 years. A positive reaction with S-100 protein, d smooth muscle actin, and CD 34 was immunohistochemically detected in chondromyxoid fibroma tissue. In chondromyxoid fibroma, the prognosis is favorable. Recurrence of the tumor is observed in 15% of the surgically treated cases.