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Review
. 2007 Aug 1;4(4):367-9.
doi: 10.1513/pats.200703-038BR.

Outcome measures for development of new therapies in cystic fibrosis: are we making progress and what are the next steps?

Bonnie W Ramsey  1
Affiliations
Review

Outcome measures for development of new therapies in cystic fibrosis: are we making progress and what are the next steps?

Bonnie W Ramsey. Proc Am Thorac Soc. .
No abstract available

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References

    1. Gibson RL, Burns JL, Ramsey BW. Pathophysiology and management of pulmonary infections in cystic fibrosis. Am J Respir Crit Care Med 2003;168:918–951. - PubMed
    1. Fuchs HJ, Borowitz DS, Christiansen DH, Morris EM, Nash ML, Ramsey BW, Rosenstein BJ, Smith AL, Wohl ME. Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. N Engl J Med 1994;331:637–642. - PubMed
    1. Ramsey BW, Pepe MS, Quan JM, Otto KL, Montgomery AB, Williams-Warren J, Vasiljev KM, Borowitz D, Bowman CM, Marshall BC, et al. Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. N Engl J Med 1999;340:23–30. - PubMed
    1. Gibson RL, Retsch-Bogart GZ, Oermann C, Milla C, Pilewski J, Daines C, Ahrens R, Leon K, Cohen M, McNamara S, et al. Microbiology, safety, and pharmacokinetics of aztreonam lysinate for inhalation in patients with cystic fibrosis. Pediatr Pulmonol 2006;41:656–665. - PubMed
    1. Deterding R, Retsch-Bogart G, Milgram L, Gibson R, Daines C, Zeitlin PL, Milla C, Marshall B, Lavange L, Engels J, et al. Safety and tolerability of denufosol tetrasodium inhalation solution, a novel P2Y2 receptor agonist: results of a phase 1/2 multicenter study in mild to moderate cystic fibrosis. Pediatr Pulmonol 2005;39:339–348. - PubMed

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