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. 2007 Aug 16;9(17):3255-7.
doi: 10.1021/ol0711974. Epub 2007 Jul 21.

Synthesis of santiagonamine

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Synthesis of santiagonamine

Michael D Markey et al. Org Lett. .

Abstract

The first total synthesis of santiagonamine (1) is achieved in 12 steps from isovanillin. A palladium-catalyzed Ullmann cross-coupling reaction and a photocyclization are the key steps in the synthesis.

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