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. 2007 Jul 20:5:81.
doi: 10.1186/1477-7819-5-81.

Gastric carcinoma: review of the results of treatment in a community teaching hospital

Vincent H Heemskerk  1 , Fanneke Lentze, Karel W E Hulsewé, Ton G M Hoofwijk
Affiliations

Gastric carcinoma: review of the results of treatment in a community teaching hospital

Vincent H Heemskerk et al. World J Surg Oncol. .

Abstract

Background: The aim of this study is to provide data on long term results of gastric cancer surgery and in particular the D1 gastric resection.

Methods: In the period 1992-2004, 235 male and female patients with a median age of 69 and 70 years respectively, were included with a stage I through IV gastric carcinoma, of which 37% was stage IV disease. Whenever possible a gastric resection was performed. In case of obstructive tumour growth palliation was provided by means of a gastro-enterostomy.

Results: Gastrectomy with curative intent was achieved in 50%, palliative resection in 22%, palliative surgery (gastro-enterostomy) in 10% and in 18% irresectability led to surgical exploration only. Patients in the curative intent group demonstrated a 47% survival after 5 years and up to 34% after 10 years. However metastases where seen in 32% of the patients after gastrectomy with curative intent. After palliative resection one year survival was 57%, whereas 19% survived more than 3 years. Overall postoperative morbidity and mortality rates were 40% and 13% respectively.

Conclusion: Long term survival after surgery for gastric cancer is poor and is improved by early detection and radical resection. However, palliative resection showed improved survival compared to gastro-enterostomy alone or no resection at all which may be an effect of adjuvant therapy.

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Figures

Figure 1
Figure 1
Survival in months of all gastric cancer patients divided per stage.
Figure 2
Figure 2
Disease free survival in months of all gastric cancer patients divided per stage.
Figure 3
Figure 3
Survival in years of gastric cancer patients divided per stage in a neighbouring region in the Netherlands.
Figure 4
Figure 4
Survival in months of all gastric cancer patients divided per treatment group.
See this image and copyright information in PMC

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