Prion disease
- PMID: 17659192
- DOI: 10.1016/j.ncl.2007.03.006
Prion disease
Abstract
Prion diseases are a unique group of neurologic diseases caused by an abnormal protein conformation. Prion diseases encompass genetic, sporadic, iatrogenic, and acquired conditions in humans and other mammals. Although they are relatively rare, they produce a diverse array of symptoms, uniformly are fatal, and provide important information about proteins and degenerative neurobiology in addition to lessons about animal and human food chains.
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