Review
doi: 10.1016/j.det.2007.04.001.
The melanocyte and the epidermal melanin unit: an expanded concept
Affiliations
- PMID: 17662893
- DOI: 10.1016/j.det.2007.04.001
Item in Clipboard
Review
The melanocyte and the epidermal melanin unit: an expanded concept
Dermatol Clin.
2007 Jul.
Abstract
There are many mechanisms by which melanocytes, keratinocytes, and Langerhans cells interact within the epidermis. Inflammatory mediators affect melanocyte function and melanogenic agents such as alpha-MSH alter the functions of keratinocytes and Langerhans cells. The epidermal melanin unit is better labeled the KLM unit.
Similar articles
-
Melanocytes as "sensory" and regulatory cells in the epidermis.J Theor Biol. 1993 Sep 7;164(1):103-20. doi: 10.1006/jtbi.1993.1142. J Theor Biol. 1993. PMID: 8264240 Review.
-
Advances in melanocyte basic science research.Dermatol Clin. 2007 Jul;25(3):283-91, vii. doi: 10.1016/j.det.2007.04.010. Dermatol Clin. 2007. PMID: 17662894 Review.
-
Melanocytes expressing MC1R polymorphisms associated with red hair color have altered MSH-ligand activated pigmentary responses in coculture with keratinocytes.J Cell Physiol. 2008 May;215(2):344-55. doi: 10.1002/jcp.21318. J Cell Physiol. 2008. PMID: 17960564
-
Skin aging and natural photoprotection.Micron. 2004;35(3):185-91. doi: 10.1016/j.micron.2003.11.005. Micron. 2004. PMID: 15036273 Review.
-
The antimicrobial properties of melanocytes, melanosomes and melanin and the evolution of black skin.J Theor Biol. 2001 Jul 21;211(2):101-13. doi: 10.1006/jtbi.2001.2331. J Theor Biol. 2001. PMID: 11419954 Review.
Cited by
-
N-tert-Butylhydroxylamine promotes melanin production in oxidative stress conditions through the MITF signaling pathway.Arch Dermatol Res. 2025 Feb 28;317(1):508. doi: 10.1007/s00403-025-04054-9. Arch Dermatol Res. 2025. PMID: 40019606
-
The etiology and molecular genetics of human pigmentation disorders.Wiley Interdiscip Rev Dev Biol. 2013 May-Jun;2(3):379-92. doi: 10.1002/wdev.72. Epub 2012 May 17. Wiley Interdiscip Rev Dev Biol. 2013. PMID: 23799582 Free PMC article. Review.
-
In vivo identification of solar radiation-responsive gene network: role of the p38 stress-dependent kinase.PLoS One. 2010 May 21;5(5):e10776. doi: 10.1371/journal.pone.0010776. PLoS One. 2010. PMID: 20505830 Free PMC article. Clinical Trial.
-
Roles of UVA radiation and DNA damage responses in melanoma pathogenesis.Environ Mol Mutagen. 2018 Jun;59(5):438-460. doi: 10.1002/em.22176. Epub 2018 Feb 21. Environ Mol Mutagen. 2018. PMID: 29466611 Free PMC article. Review.
-
Kaposi's Sarcoma-Associated Herpesvirus Subversion of the Anti-Inflammatory Response in Human Skin Cells Reveals Correlates of Latency and Disease Pathogenesis.J Skin Cancer. 2014;2014:246076. doi: 10.1155/2014/246076. Epub 2014 Feb 17. J Skin Cancer. 2014. PMID: 24701351 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
