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Review
. 2007;7(4):254-64.
doi: 10.1002/tcr.20119.

Marine cytotoxic macrolides haterumalides and biselides, and related natural products

Hideo Kigoshi  1 , Ichiro Hayakawa
Affiliations
Free article
Review

Marine cytotoxic macrolides haterumalides and biselides, and related natural products

Hideo Kigoshi et al. Chem Rec. 2007.
Free article

Abstract

Marine animals and plants are rich sources of bioactive natural products. Haterumalides and biselides, isolated from Okinawan marine animals, are 14-membered macrolides with strong cytotoxicity against human cancer cell lines. This review highlights the isolation, structures, bioactivities, and total synthesis of haterumalides, biselides, and related natural products.

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