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Case Reports
. 2007 Sep;18(8):973-6.
doi: 10.1097/CAD.0b013e3280e9496d.

Oxaliplatin-induced immune hemolytic anemia: a case report and review of the literature

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Case Reports

Oxaliplatin-induced immune hemolytic anemia: a case report and review of the literature

Francesc Cobo et al. Anticancer Drugs. 2007 Sep.

Abstract

We report a 59-year-old woman diagnosed with metastasic colorectal cancer who developed immune hemolytic anemia during FOLFOX chemotherapy (oxaliplatin/leucovorin/5-fluorouracil). Immunohematologic studies demonstrated that immune hemolysis was oxaliplatin-mediated. On the basis of this case and in a review of the literature in which 13 cases of previously reported oxaliplatin-induced immune cytopenia have been identified, we suggest some clinical clues regarding the use of oxaliplatin in cancer patients.

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