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Comparative Study
. 2007 Aug 20;97(4):574-5; author reply 576.
doi: 10.1038/sj.bjc.6603911. Epub 2007 Jul 31.

Evidence for heterogeneous nuclear ribonucleoprotein K overexpression in oral squamous cell carcinoma

Comparative Study

Evidence for heterogeneous nuclear ribonucleoprotein K overexpression in oral squamous cell carcinoma

P Roychoudhury et al. Br J Cancer. .
No abstract available

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Figures

Figure 1
Figure 1
(A) Wide box representation of hnRNP K mRNA expression in cancerous and noncancerous oral tissues. Cancer tissues showed significantly lower level of ΔCT or higher level of hnRNP K mRNA expression levels compared to noncancerous tissues (P<0.001). (B) Relative level of hnRNP K mRNA expression in different histological grades of oral SCC with respect to normal oral tissue. W.D, M.D-P.D represent well, moderately to poorly differentiated oral SCC tissues. Values are means and s.d. from n=15 (M.D+P.D) and n=11(W.D) samples.

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References

    1. Carpenter B, MacKay C, Alnabulsi A, MacKay M, Telfer C, Melvin WT, Murray GI (2006a) The roles of heterogeneous nuclear ribonucleoproteins in tumour development and progression. Biochim Biophys Acta 1765: 85–100 - PubMed
    1. Carpenter B, McKay M, Dundas SR, Lawrie LC, Telfer C, Murray GI (2006b) Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localised and is associated with poor prognosis in colorectal cancer. Br J Cancer 95: 921–927 - PMC - PubMed
    1. Moumen A, Masterson P, O'Connor MJ, Jackson SP (2005) hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage. Cell 123: 1065–1078 - PubMed

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