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Comparative Study
. 2007 Jun;39(2):71-4.

Retrospective analysis comparing hollow fiber and silicone membrane oxygenators for neonates on ECMO

Brian Mejak  1 , Carmen Giacomuzzi, Eileen Heller, Xiaomang You, Ross Ungerleider, Irving Shen
Affiliations
Comparative Study

Retrospective analysis comparing hollow fiber and silicone membrane oxygenators for neonates on ECMO

Brian Mejak et al. J Extra Corpor Technol. 2007 Jun.

Abstract

There is little information showing the use of microporous polypropylene hollow fiber oxygenators during extra-corporeal life support (ECLS). Recent surveys have shown increasing use of these hollow fibers amongst ECLS centers in the United States. We performed a retrospective analysis comparing the Terumo BabyRx hollow fiber oxygenator to the Medtronic 800 silicone membrane oxygenator on 14 neonatal patients on extracorporeal membrane oxygenation (ECMO). The aim of this study was to investigate the similarities and differences when comparing pressure drops, prime volumes, oxygenator endurance, and gas transfer capabilities between the two groups.

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Conflict of interest statement

The senior author has stated that authors have reported no material, financial or other relationship with any healthcare-related business or other entity whose products or services are discussed in this paper.

Editor’s Note: The BabyRx Hollowfiber oxygenator is approved by the FDA for up to six hours of use. Use beyond six hours is off label.

Figures

Figure 1.
Figure 1.
FiO2 requirements during the first 72 hours of ECMO support. Hours in which statistical significance is shown between the two groups are noted by asterisks.
Figure 2.
Figure 2.
Sweep requirements during the first 72 hours of ECMO support. Hours in which statistical significance is shown between the two groups are noted by asterisks.
Figure 3.
Figure 3.
Transmembrane pressure comparison during the first 72 hours of ECMO support. All values show statistical significance (p < .05).
See this image and copyright information in PMC

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References

    1. Searles B, Gunst G, Terry B, et al. . 2004 Survey of ECMO in the neonate after open heart surgery: Circuitry and team roles. J Extra Corpor Technol. 2005;37:351–4. - PMC - PubMed
    1. Groom RC, Froebe S, Martin J, et al. . Update on pediatric perfusion practice in North America: 2005 survey. J Extra Corpor Technol. 2005;37:343–50. - PMC - PubMed
    1. Lawson DS, Walczak R, Lawson A, et al. . North American neonatal extracorporeal membrane oxygenation (ECMO) devices: 2002 survey results. J Extra Corpor Technol. 2004;36:16–21. - PubMed
    1. Walczak R, Lawson DS, Kaemmer D, et al. . Evaluation of a preprimed microporous hollow-fiber membrane for rapid response neonatal extracorporeal membrane oxygenation. Perfusion. 2005;20:269–75. - PubMed
    1. Gu YJ, Boonstra PW, Graaff R, et al. . Pressure drop, shear stress, and activation of leukocytes during cardiopulmonary bypass: A comparison between hollow fiber and flat sheet membrane oxygenators. Artif Organs. 2000;24:43–8. - PubMed

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