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. 2007;117(1-4):146-57.
doi: 10.1159/000103175.

Evolutionary conservation of alternative splicing in chicken

S Katyal  1 , Z Gao, R-Z Liu, R Godbout
Affiliations

Evolutionary conservation of alternative splicing in chicken

S Katyal et al. Cytogenet Genome Res. 2007.

Abstract

Alternative splicing represents a source of great diversity for regulating protein expression and function. It has been estimated that one-third to two-thirds of mammalian genes are alternatively spliced. With the sequencing of the chicken genome and analysis of transcripts expressed in chicken tissues, we are now in a position to address evolutionary conservation of alternative splicing events in chicken and mammals. Here, we compare chicken and mammalian transcript sequences of 41 alternatively-spliced genes and 50 frequently accessed genes. Our results support a high frequency of splicing events in chicken, similar to that observed in mammals.

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