Genetic variation and phylogenetic analysis of 22 French isolates of equine arteritis virus
- PMID: 17680321
- DOI: 10.1007/s00705-007-1040-z
Genetic variation and phylogenetic analysis of 22 French isolates of equine arteritis virus
Abstract
Genetic variation and phylogenetic relationships among 22 French isolates of equine arteritis virus (EAV) obtained over four breeding seasons (2001-2004) were determined by sequencing open reading frames (ORFs) 2a-7. The ORFs 2a-7 of 22 isolates differed from the prototype virulent Bucyrus strain of EAV by between 14 (99.5% identity) and 328 (88.7% identity) nucleotides, and differed from each other by between 0 (100% identity) and 346 (88.1% identity) nucleotides, confirming genetic diversity among EAV strains circulating in France. Phylogenetic analysis based on the partial ORF5 sequences (nucleotides 11296-11813) of 22 French isolates and 216 additional EAV strains available in GenBank clustered the global isolates of EAV into two distinct groups: North American and European. The latter could be further divided into two large subgroups: European subgroup 1 (EU-1) and European subgroup 2 (EU-2). Phylogenetic analysis based on 100 EAV ORF3 sequences yielded similar results. Of the 22 French EAV isolates, the 11 isolates obtained before January 28, 2003 clustered with either the EU-1 (9 isolates) or EU-2 (2 isolates) subgroup. In contrast, by the criteria used in this study, the 11 isolates obtained after January 30, 2003 belong to the North American group, strongly suggesting that these strains were recently introduced into France.
Similar articles
-
A novel subgroup among genotypes of equine arteritis virus: genetic comparison of 40 strains.J Vet Med B Infect Dis Vet Public Health. 2005 Apr;52(3):112-8. doi: 10.1111/j.1439-0450.2005.00833.x. J Vet Med B Infect Dis Vet Public Health. 2005. PMID: 15876222
-
Molecular epizootiology of equine arteritis virus isolates from Poland.Vet Microbiol. 2008 Mar 18;127(3-4):392-8. doi: 10.1016/j.vetmic.2007.09.006. Epub 2007 Sep 19. Vet Microbiol. 2008. PMID: 17964086
-
Extended phylogeny of the equine arteritis virus sequences including South American sequences.Intervirology. 2011;54(1):30-6. doi: 10.1159/000318925. Epub 2010 Aug 6. Intervirology. 2011. PMID: 20689314
-
[Equine arteritis virus: clinical symptoms and prevention].Tijdschr Diergeneeskd. 1997 Jan 1;122(1):2-7. Tijdschr Diergeneeskd. 1997. PMID: 9012008 Review. Dutch.
-
The immune response to equine arteritis virus: potential lessons for other arteriviruses.Vet Immunol Immunopathol. 2004 Dec 8;102(3):107-29. doi: 10.1016/j.vetimm.2004.09.003. Vet Immunol Immunopathol. 2004. PMID: 15507299 Review.
Cited by
-
Combination of an unbiased amplification method and a resequencing microarray for detecting and genotyping equine arteritis virus.J Clin Microbiol. 2015 Jan;53(1):287-91. doi: 10.1128/JCM.01935-14. Epub 2014 Oct 22. J Clin Microbiol. 2015. PMID: 25339390 Free PMC article.
-
Re-emergence of a genetic outlier strain of equine arteritis virus: Impact on phylogeny.Virus Res. 2015 Apr 16;202:144-50. doi: 10.1016/j.virusres.2014.12.009. Epub 2014 Dec 17. Virus Res. 2015. PMID: 25527462 Free PMC article.
-
Development and characterization of an infectious cDNA clone of the modified live virus vaccine strain of equine arteritis virus.Clin Vaccine Immunol. 2012 Aug;19(8):1312-21. doi: 10.1128/CVI.00302-12. Epub 2012 Jun 27. Clin Vaccine Immunol. 2012. PMID: 22739697 Free PMC article.
-
Intrahost Selection Pressure Drives Equine Arteritis Virus Evolution during Persistent Infection in the Stallion Reproductive Tract.J Virol. 2019 May 29;93(12):e00045-19. doi: 10.1128/JVI.00045-19. Print 2019 Jun 15. J Virol. 2019. PMID: 30918077 Free PMC article.
-
An Overview of Infectious and Non-Infectious Causes of Pregnancy Losses in Equine.Animals (Basel). 2024 Jul 2;14(13):1961. doi: 10.3390/ani14131961. Animals (Basel). 2024. PMID: 38998073 Free PMC article. Review.
Publication types
MeSH terms
Associated data
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
LinkOut - more resources
Full Text Sources