Perceptual organization by proximity and similarity in schizophrenia

Abstract

Perceptual organization represents a basic and essential function that occurs at an intermediate level of visual processing. Much of the previous research on perceptual organization in schizophrenia employed indirect measurements, or included factors beyond sensory processing. The aims of the present study were to determine the integrity of perceptual organization in schizophrenia, as well as to determine the stimulus duration necessary to perform perceptual organization. Psychophysical measurements were compared between patients with schizophrenia and matched control subjects. Participants viewed dot patterns briefly presented on a computer monitor, and indicated whether stimuli appeared grouped as vertical or horizontal lines. Grouping was based upon either relative proximity or similarity in color. Across trials, relative proximity or color similarity was progressively reduced until stimuli became bi-stable (perceived as either of two patterns of grouping), establishing the grouping threshold. In separate conditions, stimuli were immediately followed by a mask to limit processing. Stimulus duration was progressively reduced until stimuli became bi-stable, establishing the critical stimulus duration (CSD). Schizophrenia patients demonstrated elevated grouping thresholds for grouping by proximity as well as color similarity. In addition, CSD was significantly extended for the schizophrenia group, with a nearly four-fold increase in duration of processing. These results provide direct evidence of impairment in schizophrenia for perceptual organization based upon spatial relationships and feature similarity, and suggest deficits in low-level perceptual organization processes. Although this study did not directly investigate the physiological correlates underlying perceptual impairments, these results are consistent with a theory of impaired lateral connections within visual cortical areas in schizophrenia.

Fig. 1

Examples of stimuli for the proximity condition. Top and bottom rows correspond to the vertical and horizontal conditions, respectively. Relative proximity of 45.3, 34.7, 22.9, and 10.6% corresponds to a progressive decrease in grouping cue strength.

Fig. 2

Examples of stimuli for the color similarity condition. Similarity of 100, 95, 90, and 85% depicts the percentage of elements sharing color along the vertical (top row) or horizontal (bottom row) orientations.

Fig. 3

Performance for (A) proximity grouping thresholds, (B) proximity critical stimulus duration for perceptual grouping, (C) color similarity grouping thresholds, and (D) color similarity critical stimulus duration. Each circle represents an individual subject. Bars show the group mean.