What is the true risk of a pharmacokinetic drug-drug interaction?

Editorial

Uwe Fuhr. Eur J Clin Pharmacol. 2007 Oct.

. 2007 Oct;63(10):897-9.

doi: 10.1007/s00228-007-0357-6.

No abstract available

Comment on

Tenofovir comedication does not impair the steady-state pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected adults.
von Hentig N, Dauer B, Haberl A, Klauke S, Lutz T, Staszewski S, Harder S. von Hentig N, et al. Eur J Clin Pharmacol. 2007 Oct;63(10):935-40. doi: 10.1007/s00228-007-0344-y. Epub 2007 Jul 31. Eur J Clin Pharmacol. 2007. PMID: 17665183 Clinical Trial.
Voriconazole and fluconazole increase the exposure to oral diazepam.
Saari TI, Laine K, Bertilsson L, Neuvonen PJ, Olkkola KT. Saari TI, et al. Eur J Clin Pharmacol. 2007 Oct;63(10):941-9. doi: 10.1007/s00228-007-0350-0. Epub 2007 Aug 4. Eur J Clin Pharmacol. 2007. PMID: 17676319 Clinical Trial.
Interaction between a commercially available St. John's wort product (Movina) and atorvastatin in patients with hypercholesterolemia.
Andrén L, Andreasson A, Eggertsen R. Andrén L, et al. Eur J Clin Pharmacol. 2007 Oct;63(10):913-6. doi: 10.1007/s00228-007-0345-x. Epub 2007 Aug 15. Eur J Clin Pharmacol. 2007. PMID: 17701167 Clinical Trial.