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. 2007 Sep;36(8):501-4.
doi: 10.1111/j.1600-0714.2007.00534.x.

Immunohistochemical characterization of capsular cells in neuromuscular spindles of the neck

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Immunohistochemical characterization of capsular cells in neuromuscular spindles of the neck

Asterios Triantafyllou. J Oral Pathol Med. 2007 Sep.

Abstract

Background: To identify capsular components of neuromuscular spindles in man by means of immunohistochemistry.

Methods: Investigation of histologically observed neuromuscular spindles in surgical specimens with the use of markers for sheath cells and basement membranes.

Results: Epithelial membrane antigen and CD34 immunoreactivities were found in the outer and inner capsular layers, respectively. S-100 protein was not expressed in the capsules and there was more collagen type IV than laminin.

Conclusions: Cells resembling perineurial cells and endoneurial fibroblasts, and basement membrane rich in collagen type IV comprise the capsules of neuromuscular spindles.

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