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Review
. 2007 Aug;7(4):314-20.
doi: 10.1007/s11892-007-0051-1.

Alginate-based encapsulation of cells: past, present, and future

Heiko Zimmermann  1 , Stephen G Shirley, Ulrich Zimmermann
Affiliations
Review

Alginate-based encapsulation of cells: past, present, and future

Heiko Zimmermann et al. Curr Diab Rep. 2007 Aug.

Abstract

Replacing dysfunctional endocrine tissues (eg, islets) with healthy, nonautologous material protected against the immune defense of the patient could soon become a reality. Recent advances have resulted in the development of alginate-based microcapsules that meet the demands of biocompatibility, long-term integrity, and function. Focus on the development of good manufacturing practice-conforming microfluidic chip technology for generation of immunoisolated transplants and on cryopreservation technology will bring the cell-based therapy to the market and clinics.

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References

    1. Biomacromolecules. 2005 Mar-Apr;6(2):1031-40 - PubMed
    1. Science. 1980 Nov 21;210(4472):908-10 - PubMed
    1. Int J Immunopathol Pharmacol. 2005 Oct-Dec;18(4):677-82 - PubMed
    1. Eur Biophys J. 2004 Feb;33(1):50-8 - PubMed
    1. Diabetes. 2005 Mar;54(3):687-93 - PubMed

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