[Diagnosis using monoclonal antibody imaging in the clinical follow-up of colorectal cancer]
- PMID: 1768746
[Diagnosis using monoclonal antibody imaging in the clinical follow-up of colorectal cancer]
Abstract
A total of 44 patients with a range of ages between 34 and 72 were studied by immunoscintigraphy. They have surgical treatment for colon and rectum carcinomas. The immunoradiotracer used was a cocktail of F(ab')2 monoclonal-antibodies anti-CEA and CA 19.9. Planar images were obtained 4th, 6th, and 10th days postinjection. In some cases we used digital subtraction of image. Both CEA and CA 19.9 tumor markers were measured in patients serum. The method shows a global high sensitivity (88%), and specificity (92%).
Similar articles
-
[Comparative study of CEA antibody scan and computed tomography scan in the follow-up of patients with colorectal cancer].Rev Esp Med Nucl. 2002 Sep-Oct;21(5):349-55. Rev Esp Med Nucl. 2002. PMID: 12236910 Spanish.
-
Current status of immunoscintigraphy in colorectal cancer--results of 5 years' clinical experiences.Eur J Surg Oncol. 1990 Aug;16(4):312-8. Eur J Surg Oncol. 1990. PMID: 2199223
-
Imaging of pancreatic and colorectal cancer using antibody fragments: a preliminary evaluation.Eur J Surg Oncol. 1988 Oct;14(5):393-8. Eur J Surg Oncol. 1988. PMID: 3181442
-
Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab')2.Int J Rad Appl Instrum B. 1991;18(1):51-2. doi: 10.1016/0883-2897(91)90046-n. Int J Rad Appl Instrum B. 1991. PMID: 2010306 Review.
-
In-111 monoclonal antibody immunoscintigraphy of colorectal cancer.Cancer Treat Res. 1990;51:293-312. doi: 10.1007/978-1-4613-1497-4_15. Cancer Treat Res. 1990. PMID: 1977451 Review. No abstract available.
MeSH terms
Substances
LinkOut - more resources
Medical