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Review
. 2007 Oct;7(5):478-83.
doi: 10.1016/j.coph.2007.07.004. Epub 2007 Aug 6.

Newly discovered respiratory viruses: significance and implications

Jeffrey S Kahn  1
Affiliations
Review

Newly discovered respiratory viruses: significance and implications

Jeffrey S Kahn. Curr Opin Pharmacol. 2007 Oct.

Abstract

With the recent advances in molecular biology and the ability to amplify viral genomes in a non-sequence-dependent manner, several previously unidentified human respiratory viruses have been discovered. There are accumulating data that some of these new pathogens are responsible for a substantial proportion of respiratory tract diseases, particularly in children. This review will focus on several of these newly identified pathogens for which there are clinical data implicating a role of these viruses in respiratory tract disease specifically, human metapneumovirus, human coronaviruses NL63 and HKU1, and the human bocavirus. Antivirals and effective vaccines for these new agents may decrease the burden of respiratory tract diseases.

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References

    1. Ruiz M., Ewig S., Marcos M.A., Martinez J.A., Arancibia F., Mensa J., Torres A. Etiology of community-acquired pneumonia: impact of age, comorbidity, and severity. Am J Respir Crit Care Med. 1999;160:397–405. - PubMed
    1. File T.M. Community-acquired pneumonia. Lancet. 2003;362:1991–2001. - PMC - PubMed
    1. Louie J.K., Hacker J.K., Gonzales R., Mark J., Maselli J.H., Yagi S., Drew W.L. Characterization of viral agents causing acute respiratory infection in a San Francisco University Medical Center Clinic during the influenza season. Clin Infect Dis. 2005;41:822–828. - PMC - PubMed
    1. Davies H.D., Matlow A., Petric M., Glazier R., Wang E.E. Prospective comparative study of viral, bacterial and atypical organisms identified in pneumonia and bronchiolitis in hospitalized Canadian infants. Pediatr Infect Dis J. 1996;15:371–375. - PubMed
    1. Wright A.L., Taussig L.M., Ray C.G., Harrison H.R., Holberg C.J. The Tucson Children's Respiratory Study. II. Lower respiratory tract illness in the first year of life. Am J Epidemiol. 1989;129:1232–1246. - PubMed