Homocysteine-lowering vitamins and cardiovascular mortality: are they really effective?
- PMID: 17689750
- DOI: 10.1016/j.ijcard.2007.05.044
Homocysteine-lowering vitamins and cardiovascular mortality: are they really effective?
Abstract
In the light of current data obtained from prospective outcome studies, we believe that it is premature to support the use of homocysteine-lowering vitamins including folic acid in patients with established coronary artery disease in order to improve cardiovascular outcomes. We think that future large-scale epidemiological trials with very long-term follow-up periods will probably solve this dilemma.
Comment on
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Effect of folic acid treatment on carotid intima-media thickness of patients with coronary disease.Int J Cardiol. 2007 Jun 12;118(3):345-9. doi: 10.1016/j.ijcard.2006.07.031. Epub 2006 Oct 17. Int J Cardiol. 2007. PMID: 17052775 Clinical Trial.
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