[The use of Emdogain in periodontal and osseous regeneration]

Abstract

The goal of regenerative periodontal therapy is the reconstitution of the lost periodontal structures (i. e. the new formation of root cementum, periodontal ligament and alveolar bone). Results from basic research have pointed to the important role of an enamel matrix protein derivative (EMD) in periodontal wound healing. Histological results from experiments in animals and from human case reports have shown that treatment with EMD promotes periodontal regeneration. Moreover, clinical studies have indicated that treatment with EMD positively influences periodontal wound healing in humans. The goal of the current overview is to present the clinical indications for regenerative therapy with EMD based on the existing evidence.