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Review
. 2007 Sep;18(7):280-5.
doi: 10.1016/j.tem.2007.07.004. Epub 2007 Aug 10.

Pathophysiology and types of dyslipidemia in PCOS

Evanthia Diamanti-Kandarakis  1 , Athanasios G Papavassiliou, Stylianos A Kandarakis, George P Chrousos
Affiliations
Review

Pathophysiology and types of dyslipidemia in PCOS

Evanthia Diamanti-Kandarakis et al. Trends Endocrinol Metab. 2007 Sep.

Abstract

Polycystic ovary syndrome (PCOS) is an endocrinopathy that affects women of reproductive age. PCOS shares components with the metabolic syndrome and has broad health implications. Lipid abnormalities, including elevated low-density lipoprotein (LDL), triglyceride levels and decreased high-density lipoprotein (HDL), are often found in women with PCOS. It is clear that obesity, insulin resistance and hyperandrogenism coexist in PCOS, and have independent and interactive effects on dyslipidemia, although the mechanisms of these interactions remain elusive. Here, we review the types and pathophysiology of dyslipidemia associated with PCOS and its related conditions.

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