GRASPing unconventional secretion
- PMID: 17693251
- DOI: 10.1016/j.cell.2007.07.030
GRASPing unconventional secretion
Abstract
GRASP proteins associate with the Golgi apparatus and have been implicated in the stacking of Golgi cisternae, vesicle tethering, and mitotic progression, but their specific functions are unclear. In this issue, Kinseth et al. (2007) show unexpectedly that a GRASP homolog is required for an unconventional secretory pathway that bypasses the usual route for Golgi-dependent membrane traffic.
Comment on
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The Golgi-associated protein GRASP is required for unconventional protein secretion during development.Cell. 2007 Aug 10;130(3):524-34. doi: 10.1016/j.cell.2007.06.029. Epub 2007 Jul 26. Cell. 2007. PMID: 17655921
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