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Review
. 2007 Aug 10;130(3):409-11.
doi: 10.1016/j.cell.2007.07.031.

Bone weighs in on obesity

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Free article
Review

Bone weighs in on obesity

Clay F Semenkovich et al. Cell. .
Free article

Abstract

Obesity, insulin resistance, and diabetes are related disorders of energy metabolism for which therapies are suboptimal. In this issue of Cell, Lee et al. (2007) demonstrate in mice that bone regulates the insulin/glucose axis and energy metabolism, providing a new framework for approaching common disorders of bioenergetics.

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  • Endocrine regulation of energy metabolism by the skeleton.
    Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, Zhang Z, Kim JK, Mauvais-Jarvis F, Ducy P, Karsenty G. Lee NK, et al. Cell. 2007 Aug 10;130(3):456-69. doi: 10.1016/j.cell.2007.05.047. Cell. 2007. PMID: 17693256 Free PMC article.

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