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. 2007 May 21:(19):1896-8.
doi: 10.1039/b702768k.

Adenosine residues in the template do not block spontaneous replication steps of RNA

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Adenosine residues in the template do not block spontaneous replication steps of RNA

Stephanie R Vogel et al. Chem Commun (Camb). .

Abstract

Sub-freezing temperatures, azabenzotriazolide activation, multiple monomer addition, and helper displacement help to overcome what seemed like an intrinsic block of adenine-templated RNA replication steps in the absence of enzymes.

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