In-vitro cultivation of human cytomegalovirus in thyroid epithelial cells
- PMID: 176966
- DOI: 10.1007/BF01318006
In-vitro cultivation of human cytomegalovirus in thyroid epithelial cells
Abstract
Several strains of human cytomegalovirus including recent isolates, were grown in epithelial cells derived from thyroid tissue. All the strains tested grew in these cultures without pre-treatment of the cells, and no difference in cytopathic effect was detected between strains of genital and non-genital origin. 4 strains of CMV were isolated directly from urine in thyroid cells; however the failure to isolate 6 further strains in these cultures from other specimens may indicate that a higher multiplicity of infection is required to infect epithelial than fibroblast cells.
Similar articles
-
Cytopathogenicity of cytomegalovirus to human ecto- and endocervical epithelial cells in vitro.Acta Cytol. 1975 Sep-Oct;19(5):473-81. Acta Cytol. 1975. PMID: 170769
-
Growth of murine cytomegalovirus in a heterologous cell system and its enhancement by 5-iodo-2'-deoxyuridine.Infect Immun. 1974 Jul;10(1):251-6. doi: 10.1128/iai.10.1.251-256.1974. Infect Immun. 1974. PMID: 4366921 Free PMC article.
-
[Comparative study of the susceptibility of human diploid cell strains to cytomegalovirus (CMV)].Rev Saude Publica. 1971 Jun;5(1):59-65. Rev Saude Publica. 1971. PMID: 4330884 Portuguese. No abstract available.
-
Infection of human amnion cells with cytomegalovirus.J Med Virol. 1978;2(4):369-75. doi: 10.1002/jmv.1890020410. J Med Virol. 1978. PMID: 215716
-
In vitro systems for the study and propagation of human papillomaviruses.Curr Top Microbiol Immunol. 1994;186:199-215. doi: 10.1007/978-3-642-78487-3_11. Curr Top Microbiol Immunol. 1994. PMID: 8205842 Review. No abstract available.
Cited by
-
Human Cytomegalovirus Productively Replicates In Vitro in Undifferentiated Oral Epithelial Cells.J Virol. 2018 Jul 31;92(16):e00903-18. doi: 10.1128/JVI.00903-18. Print 2018 Aug 15. J Virol. 2018. PMID: 29848590 Free PMC article.
-
Replication of cytomegalovirus in human epitheloid diploid cell line.Arch Virol. 1976;52(4):283-96. doi: 10.1007/BF01315617. Arch Virol. 1976. PMID: 189730
-
Viral replication in HeLa/fibroblast hybrid cells infected with human cytomegalovirus.Arch Virol. 1987;95(1-2):29-40. doi: 10.1007/BF01311332. Arch Virol. 1987. PMID: 3036044
-
Syncytium formation caused by human cytomegalovirus in human embryonic lung fibroblasts.Arch Virol. 1978;57(2):143-52. doi: 10.1007/BF01315675. Arch Virol. 1978. PMID: 208487
-
Constitutive and retinoic acid-inducible expression of cytomegalovirus immediate-early genes in human teratocarcinoma cells.J Virol. 1986 May;58(2):434-40. doi: 10.1128/JVI.58.2.434-440.1986. J Virol. 1986. PMID: 3009858 Free PMC article.