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Comment
. 2007 Aug;15(8):887-8.
doi: 10.1016/j.str.2007.07.003.

Diguanylate cyclase activation: it takes two

Ann M Stock
Free article
Comment

Diguanylate cyclase activation: it takes two

Ann M Stock. Structure. 2007 Aug.
Free article

Abstract

Characterization of an activated diguanylate cyclase reported in this issue of Structure by Wassmann et al. (2007) reveals how phosphorylation promotes dimerization necessary for synthesis of the second messenger c-di-GMP, establishes the catalytic mechanism, and identifies a widely conserved mode of product inhibition.

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