Brain glucose sensing, counterregulation, and energy homeostasis
- PMID: 17699877
- DOI: 10.1152/physiol.00010.2007
Brain glucose sensing, counterregulation, and energy homeostasis
Abstract
Neuronal circuits in the central nervous system play a critical role in orchestrating the control of glucose and energy homeostasis. Glucose, beside being a nutrient, is also a signal detected by several glucose-sensing units that are located at different anatomical sites and converge to the hypothalamus to cooperate with leptin and insulin in controlling the melanocortin pathway.
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