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Review
. 2007 Aug:22:269-78.
doi: 10.1152/physiol.00009.2007.

Activity-dependent signaling pathways controlling muscle diversity and plasticity

Stefano Schiaffino  1 , Marco Sandri, Marta Murgia
Affiliations
Free article
Review

Activity-dependent signaling pathways controlling muscle diversity and plasticity

Stefano Schiaffino et al. Physiology (Bethesda). 2007 Aug.
Free article

Abstract

A variety of fiber types with different contractile and metabolic properties is present in mammalian skeletal muscle. The fiber-type profile is controlled by nerve activity via specific signaling pathways, whose identification may provide potential therapeutic targets for the prevention and treatment of metabolic and neuromuscular diseases.

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