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. 1991 Oct;5(5):441-53.
doi: 10.1007/BF00125664.

The structure-activity relationship of inhibitors of serotonin uptake and receptor binding

C Hansch  1 , J Caldwell
Affiliations

The structure-activity relationship of inhibitors of serotonin uptake and receptor binding

C Hansch et al. J Comput Aided Mol Des. 1991 Oct.

Abstract

An analysis of five different datasets of inhibitors of serotonin uptake has yielded quantitative structure/activity relationships (QSARs) which delineate the role of steric and hydrophobic properties essential for inhibition by phenylethylamine-type analogues.

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