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. 2007 Dec;21(12):1253-5.
doi: 10.1002/ptr.2239.

Antiobesity properties of two African plants (Afromomum meleguetta and Spilanthes acmella) by pancreatic lipase inhibition

A P Ekanem  1 , M Wang, J E Simon, D A Moreno
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Antiobesity properties of two African plants (Afromomum meleguetta and Spilanthes acmella) by pancreatic lipase inhibition

A P Ekanem et al. Phytother Res. 2007 Dec.

Abstract

Ethanol extracts of seeds of Afromomum meleguetta and flower buds of Splilanthes acmella presented pancreatic lipase inhibitory activities in a concentration related manner under in vitro conditions. The two plants were extracted with 70% ethanol by sonication, fractionated on silica gel and tested at concentrations in the range 0.75-2.0 mg/mL. Lipase inhibitory activities of 90% and 40% were observed in A. meleguetta and S. acmella, respectively. The two plants have potentials as candidates for weight reduction and obesity control.

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