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. 2007 Oct 10;25(41):7014-6.
doi: 10.1016/j.vaccine.2007.07.028. Epub 2007 Aug 3.

The feasibility of HIV vaccine efficacy trials among Russian injection drug users

Chris Beyrer  1 , Stefan Baral, Alla Shaboltas, Elena Dukhovlinova, Alexey Masharsky, Sergey Verevochkin, Carl Latkin, Robert Heimer, Irving Hoffman, Andrei Kozlov
Affiliations

The feasibility of HIV vaccine efficacy trials among Russian injection drug users

Chris Beyrer et al. Vaccine. .

Abstract

IDU exposure remains a primary driver of the Russian HIV epidemic, and recent incidence data provide little evidence that this epidemic is slowing. While there are multiple important challenges that need to be further explored before starting vaccine trials, most importantly access to evidence-based drug treatment services for trial participants, the current context of high HIV incidence and low genetic diversity of HIV strains, suggests the need for intensified prevention strategies and supports the feasibility of mounting efficacy trials of HIV vaccines among IDUs in the Russian Federation.

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