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Comment

. 2007 Sep;3(9):533-5.

doi: 10.1038/nchembio0907-533.

Targeting the spliceosome

PMID: 17710096
DOI: 10.1038/nchembio0907-533

Comment

Targeting the spliceosome

Brian Rymond. Nat Chem Biol. 2007 Sep.

. 2007 Sep;3(9):533-5.

doi: 10.1038/nchembio0907-533.

Author

PMID: 17710096
DOI: 10.1038/nchembio0907-533

No abstract available

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Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.
Kaida D, Motoyoshi H, Tashiro E, Nojima T, Hagiwara M, Ishigami K, Watanabe H, Kitahara T, Yoshida T, Nakajima H, Tani T, Horinouchi S, Yoshida M. Kaida D, et al. Nat Chem Biol. 2007 Sep;3(9):576-83. doi: 10.1038/nchembio.2007.18. Epub 2007 Jul 22. Nat Chem Biol. 2007. PMID: 17643111
Splicing factor SF3b as a target of the antitumor natural product pladienolide.
Kotake Y, Sagane K, Owa T, Mimori-Kiyosue Y, Shimizu H, Uesugi M, Ishihama Y, Iwata M, Mizui Y. Kotake Y, et al. Nat Chem Biol. 2007 Sep;3(9):570-5. doi: 10.1038/nchembio.2007.16. Epub 2007 Jul 22. Nat Chem Biol. 2007. PMID: 17643112

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