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. 2007 May;35(5):443-6.

[Prevalence of abnormal glucose regulation in patients with chronic ischemic heart failure]

[Article in Chinese]
Hao Liu  1 , Jin-Ming Yu, Fang Chen, Chang-Yu Pan, Jue Li, Da-Yi Hu
Affiliations
  • PMID: 17711687

[Prevalence of abnormal glucose regulation in patients with chronic ischemic heart failure]

[Article in Chinese]
Hao Liu et al. Zhonghua Xin Xue Guan Bing Za Zhi. 2007 May.

Abstract

Objective: To investigate the prevalence of diabetes mellitus (DM) and glucose abnormalities in patients with ischemic chronic heart failure (CHF).

Methods: A total of 1004 hospitalized eligible patients from 52 hospitals in 7 Chinese cities were included in this study.

Results: In this survey, 420 out of 1004 patients had DM history (41.8%), 175 patients were newly diagnosed as DM (17.4%), 208 patients (20.7%) had impaired glucose tolerance (IGT). NYHA grade increases in proportion to severity of abnormal glucose metabolism [(r(s)) = 0.17, P = 0.001]. After adjustment of age and other factors, logistic regression analyses showed risk of suffering severe CHF symptoms (NYHA III/IV) increases with the severity of abnormal glucose metabolism: OR, 1.2, 95% CI: 0.7 - 1.7 in patients with IGT; 1.4, 95% CI: 0.9 - 2.1 in the newly diagnosed DM patients and 1.7, 95% CI: 1.2 - 2.4 in the DM history group, respectively.

Conclusions: High prevalence of abnormal glucose metabolism was observed in patients with chronic ischemic hear failure and the severity of abnormal glucose metabolism was closely related to NYHA symptom grade.

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