Are postnatal steroids ever justified to treat severe bronchopulmonary dysplasia?
- PMID: 17712183
- PMCID: PMC2675350
- DOI: 10.1136/adc.2006.106583
Are postnatal steroids ever justified to treat severe bronchopulmonary dysplasia?
Abstract
Current evidence does not favour use of corticosteroids as neurological side effects may outweigh the benefits of treatment, except perhaps in critically ill infants with respiratory failure
Conflict of interest statement
Competing interests: None.
Similar articles
-
Postnatal corticosteroids for preterm infants--do what we say, not what we do.N Engl J Med. 2004 Mar 25;350(13):1349-51. doi: 10.1056/NEJMe048031. N Engl J Med. 2004. PMID: 15044647 No abstract available.
-
Policy statement--postnatal corticosteroids to prevent or treat bronchopulmonary dysplasia.Pediatrics. 2010 Oct;126(4):800-8. doi: 10.1542/peds.2010-1534. Epub 2010 Sep 6. Pediatrics. 2010. PMID: 20819899
-
[The use of postnatal corticosteroid therapy in premature infants to prevent or treat bronchopulmonary dysplasia: current situation and recommendations].Arch Pediatr. 2010 Oct;17(10):1480-7. doi: 10.1016/j.arcped.2010.07.013. Epub 2010 Sep 22. Arch Pediatr. 2010. PMID: 20864322 French.
-
Corticosteroids in the prevention and management of bronchopulmonary dysplasia.Semin Neonatol. 2003 Feb;8(1):83-91. doi: 10.1016/s1084-2756(02)00189-6. Semin Neonatol. 2003. PMID: 12667833 Review.
-
Inhaled Drugs and Systemic Corticosteroids for Bronchopulmonary Dysplasia.Pediatr Clin North Am. 2017 Dec;64(6):1355-1367. doi: 10.1016/j.pcl.2017.08.012. Epub 2017 Oct 4. Pediatr Clin North Am. 2017. PMID: 29173790 Review.
Cited by
-
Comparing low-dose (DART) and enhanced low-dose dexamethasone regimens in preterm infants with bronchopulmonary dysplasia.Front Pediatr. 2023 Oct 31;11:1261316. doi: 10.3389/fped.2023.1261316. eCollection 2023. Front Pediatr. 2023. PMID: 38027255 Free PMC article.
-
Systemic Hydrocortisone To Prevent Bronchopulmonary Dysplasia in preterm infants (the SToP-BPD study); a multicenter randomized placebo controlled trial.BMC Pediatr. 2011 Nov 9;11:102. doi: 10.1186/1471-2431-11-102. BMC Pediatr. 2011. PMID: 22070744 Free PMC article. Clinical Trial.
-
Risk factors affecting school readiness in premature infants with respiratory distress syndrome.Pediatrics. 2009 Jul;124(1):258-67. doi: 10.1542/peds.2008-1771. Pediatrics. 2009. PMID: 19564308 Free PMC article.
-
Neonatal steroids induce a down-regulation of tenascin-C and elastin and cause a deceleration of the first phase and an acceleration of the second phase of lung alveolarization.Histochem Cell Biol. 2014 Jan;141(1):75-84. doi: 10.1007/s00418-013-1132-7. Epub 2013 Aug 4. Histochem Cell Biol. 2014. PMID: 23912843
-
Pulmonary effects of neonatal hydrocortisone treatment in ventilator-dependent preterm infants.Int J Pediatr. 2011;2011:783893. doi: 10.1155/2011/783893. Epub 2011 Dec 20. Int J Pediatr. 2011. PMID: 22229038 Free PMC article.
References
-
- Roberts D, Dalziel S. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk for preterm birth. Cochrane Database Syst Rev 20063CD004454 - PubMed
-
- Watterberg K L, Gerdes J S, Cook K L. Impaired glucocorticoid synthesis in premature infants developing chronic lung disease. Pediatr Res 200150190–195. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical