Comment on

• The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4.

  Brüstle A, Heink S, Huber M, Rosenplänter C, Stadelmann C, Yu P, Arpaia E, Mak TW, Kamradt T, Lohoff M. Brüstle A, et al. Nat Immunol. 2007 Sep;8(9):958-66. doi: 10.1038/ni1500. Epub 2007 Aug 5. Nat Immunol. 2007. PMID: 17676043
• Development, cytokine profile and function of human interleukin 17-producing helper T cells.

  Wilson NJ, Boniface K, Chan JR, McKenzie BS, Blumenschein WM, Mattson JD, Basham B, Smith K, Chen T, Morel F, Lecron JC, Kastelein RA, Cua DJ, McClanahan TK, Bowman EP, de Waal Malefyt R. Wilson NJ, et al. Nat Immunol. 2007 Sep;8(9):950-7. doi: 10.1038/ni1497. Epub 2007 Aug 5. Nat Immunol. 2007. PMID: 17676044
• Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells.

  Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F. Acosta-Rodriguez EV, et al. Nat Immunol. 2007 Sep;8(9):942-9. doi: 10.1038/ni1496. Epub 2007 Aug 5. Nat Immunol. 2007. PMID: 17676045