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. 1975 Jun;79(6):66-9.

[Effect of carbidine on the process of adrenergic neurotransmission]

[Article in Russian]
V A Arefolov, L V Panasiuk
  • PMID: 177124

[Effect of carbidine on the process of adrenergic neurotransmission]

[Article in Russian]
V A Arefolov et al. Biull Eksp Biol Med. 1975 Jun.

Abstract

Methods of physiological analysis were applied to a study of the effect of an original psychotropic agent--carbidine--on the process of adrenergic neurotransmission on a model of an isolated rat Vas deferens. The noradrenaline (NA) content was determined in the same ductus spectrofluorimetrically; the capacity of the neuroleptic to block the consumption of the exogenous NA by the tissue was also investigated. Carbidine proved to possess an adrenomimetic effect caused by it capacity to release NA, leading to a reduction of endogenous neuromediator stores.

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