[Application of ELISA for microcystins detection]
- PMID: 17712969
[Application of ELISA for microcystins detection]
Abstract
Microcystins (MCs) may be group of closely related toxic cyclic heptapeptides produced by common cyanobacteria (blue-green algae). Their toxicity could be associated with specific inhibition of intracellular protein phosphatases type-1 and type-2A (PP1 and PP2A, respectively). There are some methods for analyzing and detecting MCs in aquatic environment, such as HPLC, LC-MS, PPIA, and ELISA. This review introduces advances on MCs determined by enzyme-linked immunosorbent assay (ELISA), and estimates the prospective development of ELISA for monitoring MCs in natural waters.
Similar articles
-
[Study progress on pollution and liver cancer promotion of microcystins].Wei Sheng Yan Jiu. 2006 May;35(3):377-9. Wei Sheng Yan Jiu. 2006. PMID: 16921774 Review. Chinese.
-
[Investigation of microcystin pollution on Dong Lake, Wuhan City].Wei Sheng Yan Jiu. 2004 Jan;33(1):39-41. Wei Sheng Yan Jiu. 2004. PMID: 15098475 Chinese.
-
A protein phosphatase 2A (PP2A) inhibition assay using a recombinant enzyme for rapid detection of microcystins.Toxicon. 2008 Jun 15;51(8):1368-73. doi: 10.1016/j.toxicon.2008.03.003. Epub 2008 Mar 6. Toxicon. 2008. PMID: 18430448
-
The presence of microcystins and other cyanobacterial bioactive peptides in aquatic fauna collected from Greek freshwaters.Aquat Toxicol. 2006 Jun 10;78(1):32-41. doi: 10.1016/j.aquatox.2006.02.001. Epub 2006 Mar 15. Aquat Toxicol. 2006. PMID: 16540185
-
Recent developments in the methods of quantitative analysis of microcystins.J Biochem Mol Toxicol. 2020 Dec;34(12):e22582. doi: 10.1002/jbt.22582. Epub 2020 Jul 14. J Biochem Mol Toxicol. 2020. PMID: 32662914 Review.