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. 2007 May 28:(20):2054-6.
doi: 10.1039/b618568a.

Archaeosomes based on synthetic tetraether-like lipids as novel versatile gene delivery systems

G Réthoré  1 , T Montier, T Le Gall, P Delépine, S Cammas-Marion, L Lemiègre, P Lehn, T Benvegnu
Affiliations

Archaeosomes based on synthetic tetraether-like lipids as novel versatile gene delivery systems

G Réthoré et al. Chem Commun (Camb). .

Abstract

Novel cationic liposomes, termed "archaeosomes", based on mixtures of neutral/cationic bilayer-forming lipids and archaeobacterial synthetic tetraether-type bipolar lipids show efficient in vitro gene transfection properties and represent a new approach for modulating the lipidic membrane fluidity of the complexes they form with DNA.

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