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Review
. 2007 Aug 27;84(4):459-61.
doi: 10.1097/01.tp.0000275424.52998.ad.

Understanding FOXP3: progress towards achieving transplantation tolerance

Elaine Long  1 , Kathryn J Wood
Affiliations
Review

Understanding FOXP3: progress towards achieving transplantation tolerance

Elaine Long et al. Transplantation. .

Abstract

Regulatory T cells (Treg) suppress immune responses, making them an exciting therapeutic target for achieving operational transplant tolerance. Recent observations have identified forkhead box P3 (FOXP3) as a master gene required for the development and function of Treg. Improving our understanding of FOXP3 may facilitate methods for identifying and generating Treg.

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