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. 1976 Apr;32(4):279-84.
doi: 10.1007/BF01005310.

[Immunologic status in Hodgkin patients: correlation with Epstein-Barr virus titers]

[Article in German]
V Diehl, K Hegge, J Kalden, U Desselberger, P Krull

[Immunologic status in Hodgkin patients: correlation with Epstein-Barr virus titers]

[Article in German]
V Diehl et al. Blut. 1976 Apr.

Abstract

1. In Hodgkin's disease patient's immunological in vitro and in vivo parameters are of prognostic importance. 2. Skin test reactivity correlates to peripheral T-lymphocyte counts and Con A induced lymphoblastogenesis. 3. Con A is the most sensitive in vitro indicator for detecting latent immunodeficiency. 4. Hodgkin patients in long term remission after tumor reductive therapy exhibit a qualitative and quantitative lymphocyte defect. 5. In Hodgkin patients Herpes virus related antibody titers are elevated against Epstein Barr virus (EBV). The elevation coincides with a decreased T-cell number and function. Antibodies against other Herpes viruses (HSV, CMV, VZV) are in the normal range, when tested by the complement fixation method.

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