Predictors of ventricular dysfunction and coronary artery disease in Iranian patients with left bundle branch block

Abstract

Patients with coronary artery disease (CAD) and concomitant left bundle branch block (LBBB) have increased cardiovascular mortality rates in comparison with those with CAD but without LBBB. In patients with LBBB, therefore, the delineation of the presence and severity of CAD may be helpful in providing prognostic information. In this cross-sectional study 219 patients with LBBB and suspected CAD that underwent coronary angiography, assessed for having CAD and left ventricular (LV) dysfunction. CAD was present in 124 (56.3%) patients and left ventricular ejection fraction <50% was seen in 147 (67.1%) patients. Advanced age (p=0.001), male gender (p=0.027, OR=1.94), history of chest pain (p=0.015, OR=2.08) and LVEF <50% (p=0.026, OR=3.04) were predictors of CAD and older age (p=0.004), male gender (p=0.017, OR=2.11), history of diabetes mellitus (p=0.043, OR=1.45) and angiographically documented CAD (p=0.001, OR=3.41) were predictors of LV dysfunction.