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. 2007 Oct;45(10):3436-8.
doi: 10.1128/JCM.00973-07. Epub 2007 Aug 22.

Human immunodeficiency virus type 1 (HIV-1) plasma load discrepancies between the Roche COBAS AMPLICOR HIV-1 MONITOR Version 1.5 and the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 assays

F Damond  1 , B Roquebert, A Bénard, G Collin, M Miceli, P Yéni, F Brun-Vezinet, D Descamps
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Human immunodeficiency virus type 1 (HIV-1) plasma load discrepancies between the Roche COBAS AMPLICOR HIV-1 MONITOR Version 1.5 and the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 assays

F Damond et al. J Clin Microbiol. 2007 Oct.

Abstract

We compared plasma viral load values obtained with COBAS AMPLICOR human immunodeficiency virus type 1 (HIV-1) MONITOR version 1.5 and with COBAS TaqMan HIV-1 assays. Mean values were 4.2 and 2.9 log(10) copies/ml, respectively, showing the lack of agreement between the two assays.

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Figures

FIG. 1.
FIG. 1.
Degree of agreement in log10 copies/ml between the COBAS MONITOR 1.5 and the COBAS TaqMan assays for the 160 plasma specimens. The x axis of the Bland and Altman curves bears the mean values for each sample obtained by the two techniques. The y axis bears the differences between the values obtained by the two techniques. The solid lines represent the mean differences between the values, and the dotted lines represent the mean difference plus or minus 1.96 SD (95% limit of agreement).
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