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. 1976 Apr;37(4):1718-24.
doi: 10.1002/1097-0142(197604)37:4<1718::aid-cncr2820370417>3.0.co;2-x.

Morphologic study of virus-like particles in a case of acute leukemia

C Foa, J Foa, Y Carcassonne

Morphologic study of virus-like particles in a case of acute leukemia

C Foa et al. Cancer. 1976 Apr.

Abstract

Virus-like particles, grouped in clusters not bound by a membraine, were seen in electron micrographs of fresh leucoblasts of an acute leukemic patient. They consisted of large (100-nm diameter), round particles apparently composed of subunits. Tubular structures (30-50-nm diameter) were also seen in leucoblasts of the same patient. The two types of structures were never seen simultaneously in the same cell. The authors review the literature pertaining to the morphology of virus-like particles associated with malignant hematologic disease.

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References

    1. Ackerman, G. A. , Grasso, J. A. , and Knouff, R. A. Morphological and histochemical studies of the leukemic cells from a patient with a typical myeloblastic leukemia with special reference to intracytoplasmic mucopolysaccharide vacuoles and fibrillar formation. Blood 16: 1253–1267, 1963. - PubMed
    1. Baringer, S. R. , and Swoveland, P. Tubular aggregates in endoplasmic reticulum. Evidence against their viral nature. J. Ultrastruct. Res. 41: 270–276, 1972. - PubMed
    1. Bernhard, W. The detection and study of tumor viruses with the electron microscope. Cancer Res. 20: 712–727, 1968. - PubMed
    1. Bessis, M. , and Thierry, J. P. Etudes au microscope électronique sur les leucémies humaines. I. Les leucémies granulocytaires. Nouv. Rev. Fr. Hématol. 1: 703–728, 1961. - PubMed
    1. Chandra, S. , Buscheck, F. T. , Garon, C. , and Manaker, R. A. Propagation and micromorphology of a human leukocyte culture M1 and of cultures derived from its transplantation in hamsters. Cancer Res. 29: 1819–1838, 1967. - PubMed

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