Bacteraemia in man and animals: an overview

Abstract

Bacteraemia signifies invasion of the bloodstream by bacteria. In most systemic infections in man and animals, bacteria enter the blood at some stage during the infection and are rapidly distributed throughout the body. A wide variety of organisms have been associated with bacteraemia. Prompt detection of the aetiological agents of bacteraemia is of prime importance in clinical microbiology. There are no defined recommendations for blood cultures in animals but both conventional and improved methods are available for detection of bacteraemia in man. The consequences of bacteraemia are as diverse as the potential aetiological agents. Monoclonal antibodies to the core glycolipid (lipid A) seems very promising for the treatment of bacteraemia and septic shock caused by Gram-negative bacteria in man and animals.