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Review
. 2007 Aug;9(10):1226-35.
doi: 10.1016/j.micinf.2007.05.010. Epub 2007 May 7.

Listeria as a vaccine vector

Kevin W Bruhn  1 , Noah Craft, Jeff F Miller
Affiliations
Free article
Review

Listeria as a vaccine vector

Kevin W Bruhn et al. Microbes Infect. 2007 Aug.
Free article

Abstract

The immunostimulatory characteristics and intracellular niche of Listeria monocytogenes make it uniquely suitable for use as a live bacterial vaccine vector. Preclinical results supporting this idea, and current strategies to induce beneficial cell-mediated immunity to both infectious diseases and cancer with this vector, are discussed in this review.

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