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Review
. 2007 Aug;9(10):1208-15.
doi: 10.1016/j.micinf.2007.05.008. Epub 2007 May 7.

Innate and adaptive immune responses to Listeria monocytogenes: a short overview

Lauren A Zenewicz  1 , Hao Shen
Affiliations
Review

Innate and adaptive immune responses to Listeria monocytogenes: a short overview

Lauren A Zenewicz et al. Microbes Infect. 2007 Aug.

Abstract

The Gram-positive facultative intracellular bacterium Listeria monocytogenes is a model pathogen for elucidating important mechanisms of the immune response. Infection of mice with a sub-lethal dose of bacteria generates highly reproducible innate and adaptive immune responses, resulting in clearance of the bacteria and resistance to subsequent L. monocytogenes infection. Both the innate and adaptive immune systems are crucial to the recognition and elimination of this pathogen from the host.

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References

    1. Mackaness GB. Cellular resistance to infection. J Exp Med. 1962;116:381–406. - PMC - PubMed
    1. Conlan JW. Early pathogenesis of Listeria monocytogenes infection in the mouse spleen. J Med Microbiol. 1996;44:295–302. - PubMed
    1. Bancroft GJ, Schreiber RD, Unanue ER. Natural immunity: a T-cell-independent pathway of macrophage activation, defined in the SCID mouse. Immunol Rev. 1991;124:5–24. - PubMed
    1. Bhardwaj V, Kanagawa O, Swanson PE, Unanue ER. Chronic Listeria infection in SCID mice: requirements for the carrier state and the dual role of T cells in transferring protection or suppression. J Immunol. 1998;160:376–384. - PubMed
    1. Pamer EG, Harty JT, Bevan MJ. Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes. Nature. 1991;353:852–855. - PMC - PubMed

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