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Review
. 2007 Aug;9(10):1208-15.
doi: 10.1016/j.micinf.2007.05.008. Epub 2007 May 7.

Innate and adaptive immune responses to Listeria monocytogenes: a short overview

Lauren A Zenewicz  1 , Hao Shen
Affiliations
Review

Innate and adaptive immune responses to Listeria monocytogenes: a short overview

Lauren A Zenewicz et al. Microbes Infect. 2007 Aug.

Abstract

The Gram-positive facultative intracellular bacterium Listeria monocytogenes is a model pathogen for elucidating important mechanisms of the immune response. Infection of mice with a sub-lethal dose of bacteria generates highly reproducible innate and adaptive immune responses, resulting in clearance of the bacteria and resistance to subsequent L. monocytogenes infection. Both the innate and adaptive immune systems are crucial to the recognition and elimination of this pathogen from the host.

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