Foundations for directed alkaloid biosynthesis
- PMID: 17719485
- DOI: 10.1016/j.chembiol.2007.08.001
Foundations for directed alkaloid biosynthesis
Abstract
In this issue of Chemistry & Biology, Bernhardt and coworkers [1] assay the functional plasticity of strictosidine synthase, a gateway enzyme in the biosynthetic pathways of monoterpene indole alklaloids, and the downstream operability of the products of strictosidine synthase variants in the larger context of the plant biosynthetic pathways.
Comment on
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Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle.Chem Biol. 2007 Aug;14(8):888-97. doi: 10.1016/j.chembiol.2007.07.008. Chem Biol. 2007. PMID: 17719488 Free PMC article.
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