Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Oct;73(20):6686-90.
doi: 10.1128/AEM.01054-07. Epub 2007 Aug 24.

Zoo animals as reservoirs of gram-negative bacteria harboring integrons and antimicrobial resistance genes

Ashraf M Ahmed  1 , Yusuke Motoi, Maiko Sato, Akito Maruyama, Hitoshi Watanabe, Yukio Fukumoto, Tadashi Shimamoto
Affiliations

Zoo animals as reservoirs of gram-negative bacteria harboring integrons and antimicrobial resistance genes

Ashraf M Ahmed et al. Appl Environ Microbiol. 2007 Oct.

Abstract

A total of 232 isolates of gram-negative bacteria were recovered from mammals, reptiles, and birds housed at Asa Zoological Park, Hiroshima prefecture, Japan. Forty-nine isolates (21.1%) showed multidrug resistance phenotypes and harbored at least one antimicrobial resistance gene. PCR and DNA sequencing identified class 1 and class 2 integrons and many beta-lactamase-encoding genes, in addition to a novel AmpC beta-lactamase gene, bla(CMY-26). Furthermore, the plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr were also identified.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Ahmed, A. M., K. Furuta, K. Shimomura, Y. Kasama, and T. Shimamoto. 2006. Genetic characterization of multidrug resistance in Shigella spp. from Japan. J. Med. Microbiol. 55:1685-1691. - PubMed
    1. Bender, J. B., and S. A. Shulman. 2004. Reports of zoonotic disease outbreaks associated with animal exhibits and availability of recommendations for preventing zoonotic disease transmission from animals to people in such settings. J. Am. Vet. Med. Assoc. 224:1105-1109. - PubMed
    1. Bradford, P. A. 2001. Extended-spectrum β-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin. Microbiol. Rev. 14:933-951. - PMC - PubMed
    1. Cavaco, L. M., D. S. Hansen, A. Friis-Moller, F. M. Aarestrup, H. Hasman, and N. Frimodt-Moller. 2007. First detection of plasmid-mediated quinolone resistance (qnrA and qnrS) in Escherichia coli strains isolated from humans in Scandinavia. J. Antimicrob. Chemother. 59:804-805. - PubMed
    1. Clinical and Laboratory Standards Institute. 2002. Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals. Approved standard, 2nd ed. NCCLS document M31-A2. Clinical and Laboratory Standards Institute, Wayne, PA.

Publication types

MeSH terms

Associated data