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Review
. 1991:294:51-61.
doi: 10.1007/978-1-4684-5952-4_5.

Signal-to-noise optimization of HPLC-fluorometric systems and their application to the analysis of indoles

Affiliations
Review

Signal-to-noise optimization of HPLC-fluorometric systems and their application to the analysis of indoles

G M Anderson. Adv Exp Med Biol. 1991.

Abstract

The signal-to-noise optimization of high performance liquid chromatographic (HPLC) flow-cell fluorometric systems is described and the possibilities for further improving limits of detection for indoles is discussed. Application of HPLC-fluorometry to analyses in rat cerebrospinal fluid (CSF), human lumbar CSF, and human blood is presented. Finally, the intriguing clinical finding of hyperserotonemia in autism is discussed.

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