Revving the engine: signal transduction fuels T cell activation
- PMID: 17723208
- DOI: 10.1016/j.immuni.2007.07.008
Revving the engine: signal transduction fuels T cell activation
Abstract
For initiation of an immune response, resting T cells must reprogram their metabolism. Continuing the "From the Field" series (see Editorial [2007] 26, 131), Jones and Thompson draw attention to the importance of metabolism during T cell activation and consider how this process is regulated by receptor-mediated signal transduction.
Comment on
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The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis.Immunity. 2007 Aug;27(2):268-80. doi: 10.1016/j.immuni.2007.05.023. Epub 2007 Aug 9. Immunity. 2007. PMID: 17692540 Free PMC article.
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